America has a very serious lineup, while Panama is extremely weak. The game is being played in America, in the Atlantic, so I believe that America, playing at home, is a very clear and strong favorite. Panama lost 3-1 to Uruguay, with the score only happening in the 90+5 minute, and the xG (expected goals) was only 0.5, so I think America should win comfortably and do so convincingly.
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